RPL24

Across TCGA pan-cancer cohorts, RPL24 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RPL24 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPL24 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPL24 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where RPL24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.676	0.912	.006	20	view →
HNSC	OS	Median	All	0.833	0.608	.005	19	view →
UCEC	OS	Median	II,III,IV	1.000	0.653	.020	14	view →
LSCC	DFS	Median	All	0.918	0.397	.001	8	view →
GBM	DFS	Median	All	0.272	0.468	.005	7	view →
PDAC	DFS	Median	II,III,IV	0.791	0.714	.015	6	view →
LUAD	DFS	Median	All	0.753	0.479	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RPL24–CCRCC (OS)

Open the CCRCC breakdown →