RPL24

Across TCGA pan-cancer cohorts, RPL24 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RPL24’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL24 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

KIRC, LIHC, and HNSC are the cancer types where RPL24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.811	<.001	12	view →
LIHC	Female	II,III,IV	+0.926	<.001	9	view →
HNSC	Male	All	+0.445	<.001	7	view →
COAD	All	II,III,IV	+0.486	.001	6	view →
CHOL	Male	All	+1.816	<.001	4	view →
THCA	All	All	+0.297	<.001	4	view →
BRCA	Female	All	−0.216	.003	4	view →
KICH	Female	All	−1.024	.001	3	view →
KIRP	All	II,III,IV	+0.460	.015	3	view →
LUSC	Male	All	+0.445	<.001	3	view →
UCEC	All	All	−0.447	.026	2	view →
PRAD	All	All	+0.214	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RPL24–KIRC

Open the KIRC breakdown →