RPL23AP90

Across TCGA pan-cancer cohorts, RPL23AP90 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL23AP90 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RPL23AP90 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP90 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LUSC show a favorable association.

DLBC, CESC, and UVM are the cancer types where RPL23AP90 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Median	III,IV	0.169	0.984	.001	66	view →
CESC	DFS	Tertile	III,IV	0.194	0.654	<.001	62	view →
UVM	DFS	Tertile	III,IV	0.209	0.662	.001	32	view →
ACC	OS	Tertile	IV	0.247	0.777	<.001	32	view →
LUAD	OS	Median	All	0.880	0.787	.013	22	view →
COAD	OS	Tertile	II,III,IV	0.751	0.895	.004	20	view →
LUSC	OS	Tertile	III,IV	0.660	0.345	.006	17	view →
BRCA	DFS	Median	III,IV	0.842	0.742	.024	14	view →
THCA	DFS	Median	IV	0.577	0.932	.029	12	view →
KICH	DFS	Tertile	IV	0.317	0.923	.038	9	view →
KIRC	DFS	Quartile	All	0.916	0.736	.005	8	view →
READ	OS	Tertile	III,IV	0.456	0.945	.028	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL23AP90–DLBC (DFS)

Open the DLBC breakdown →