RPL23AP90

Across TCGA pan-cancer cohorts, RPL23AP90 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL23AP90’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RPL23AP90 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL23AP90 is over-expressed in tumor, although a few such as KICH and ESCA show the opposite, repressed pattern.

KICH, PRAD, and BRCA are the cancer types where RPL23AP90 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP90 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−0.180	.017	3	view →
PRAD	All	All	+0.155	.031	2	view →
BRCA	All	IV	+0.135	.022	2	view →
COAD	All	IV	+0.610	.048	1	view →
ESCA	All	All	−0.562	.020	1	view →
READ	Female	All	+0.465	.044	1	view →
THCA	All	IV	−0.367	.046	1	view →
CHOL	All	All	+0.302	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL23AP90–KICH

Open the KICH breakdown →