RPL23AP86

Across TCGA pan-cancer cohorts, RPL23AP86 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RPL23AP86 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RPL23AP86 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL23AP86 expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRC show a favorable association.

BLCA, LIHC, and KIRC are the cancer types where RPL23AP86 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	II,III,IV	0.671	0.552	.012	29	view →
LIHC	OS	Quartile	All	0.670	0.822	.003	21	view →
KIRC	DFS	Quartile	IV	0.777	0.265	.001	18	view →
HNSC	OS	Median	III,IV	0.259	0.382	.027	12	view →
TGCT	DFS	Quartile	All	0.529	0.731	.031	12	view →
LUSC	DFS	Tertile	III,IV	0.524	0.735	.029	10	view →
READ	OS	Median	II,III,IV	0.851	0.464	.008	9	view →
LUAD	DFS	Quartile	III,IV	0.845	0.443	.022	6	view →
SKCM	OS	Tertile	IV	0.184	0.789	.019	4	view →
MESO	OS	Median	IV	0.540	0.249	.036	3	view →
LGG	OS	Median	All	0.849	0.774	.023	3	view →
UCEC	OS	Quartile	All	0.910	0.929	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RPL23AP86–BLCA (OS)

Open the BLCA breakdown →