Across TCGA pan-cancer cohorts, RPL23AP85 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL23AP85’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RPL23AP85 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL23AP85 is over-expressed in tumor, although a few such as UCEC and LUAD show the opposite, repressed pattern.

UCEC, LUAD, and BRCA are the cancer types where RPL23AP85 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP85 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	II,III,IV	−0.160	.017	4	view →
LUAD	Female	III,IV	−0.268	.008	2	view →
BRCA	Female	II,III,IV	−0.059	.017	2	view →
KICH	All	IV	−0.220	.007	1	view →
KIRP	All	All	−0.074	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RPL23AP85 RNA expression & survival · all RPL23AP85 data types