Q-omics provides the consensus-scored RPL23AP77 profile across patient tissues and cancer cell-line models. RPL23AP77 expression is associated with patient survival in 26 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RPL23AP77 is differentially expressed in 10, with the highest sampling consensus in LUAD. Additionally, RPL23AP77 RNA expression shows 7,650 significant gene co-expression associations, with the highest sampling consensus in PAAD. Together, these results highlight KIRP, LUAD, and PAAD as cancer lineages where RPL23AP77 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL23AP77 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL23AP77 survival associations across molecular data types. RPL23AP77 RNA expression shows survival associations in the most cancer types (26). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL23AP77 RNA expression–survival associations across cancer types. High RPL23AP77 expression shows unfavorable associations in KIRP, PAAD, DLBC, UCEC, COAD and KIRC. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for RPL23AP77 RNA expression.
This table summarizes RPL23AP77 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RPL23AP77. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL23AP77 shows lower tumor expression in UCEC and higher tumor expression in LUAD, KIRC, KIRP, COAD and HNSC. The LUAD box plot shows higher RPL23AP77 RNA expression in tumor versus normal tissue (log2 FC = +1.831, t-test p < 0.001).
This table shows molecular features associated with RPL23AP77 in patient tissues and cancer cell lines. In patient samples, RPL23AP77 shows the broadest associations at the RNA and protein expression levels, with PAAD recurring as the lineage with the largest associated feature set.
