RPL23AP68

Across TCGA pan-cancer cohorts, RPL23AP68 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL23AP68 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL23AP68 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP68 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

KIRC, DLBC, and CESC are the cancer types where RPL23AP68 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.445	0.759	<.001	105	view →
DLBC	OS	Tertile	II,III,IV	0.085	0.865	<.001	75	view →
CESC	DFS	Tertile	III,IV	0.091	0.728	<.001	72	view →
KIRP	OS	Tertile	II,III,IV	0.146	0.784	<.001	72	view →
KICH	OS	Tertile	All	0.439	0.893	<.001	69	view →
BLCA	OS	Tertile	III,IV	0.512	0.670	.006	51	view →
ESCA	DFS	Tertile	III,IV	0.260	0.500	.003	48	view →
UVM	OS	Tertile	All	0.218	0.696	.014	36	view →
THCA	OS	Tertile	IV	0.483	0.897	<.001	33	view →
HNSC	OS	Tertile	IV	0.258	0.649	.006	33	view →
LIHC	OS	Tertile	All	0.624	0.794	.002	33	view →
CHOL	OS	Tertile	All	0.154	0.793	.004	27	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL23AP68–KIRC (DFS)

Open the KIRC breakdown →