RPL23AP55

Across TCGA pan-cancer cohorts, RPL23AP55 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL23AP55 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPL23AP55 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP55 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

ACC, TGCT, and BRCA are the cancer types where RPL23AP55 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	III,IV	0.065	0.489	.001	42	view →
TGCT	DFS	Tertile	III,IV	0.340	1.000	.002	36	view →
BRCA	OS	Median	All	0.690	0.474	<.001	20	view →
CESC	DFS	Median	III,IV	0.586	0.836	.009	12	view →
SARC	DFS	Median	All	0.529	0.653	.012	12	view →
SKCM	DFS	Quartile	IV	0.624	0.177	.030	9	view →
LUAD	DFS	Quartile	All	0.464	0.252	.014	8	view →
STAD	DFS	Median	III,IV	0.514	0.662	.012	8	view →
KIRP	DFS	Tertile	II,III,IV	0.868	0.646	.012	7	view →
LUSC	OS	Quartile	III,IV	0.156	0.839	.016	6	view →
KIRC	DFS	Quartile	III,IV	0.789	0.625	.026	6	view →
DLBC	OS	Median	IV	0.342	0.930	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL23AP55–ACC (DFS)

Open the ACC breakdown →