RPL23AP53

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL23AP53 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL23AP53-associated genes across cancer lineages are MIR8053, MIR508, and MIR487B. Each is linked with RPL23AP53 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL23AP53-to-partner and partner-to-RPL23AP53 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23AP53→partner) and Y-score (partner→RPL23AP53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR8053 →+0.389+3.997<.001.00932
LUSCMIR508 →+0.332+7.924<.001.00831
LUSCMIR487B →+0.442+7.924<.001.00831
LUSCMIR892A →+0.463+7.924<.001.00831
LUSCRNU2-26P →+0.288+7.924<.001.00831
LUSCUSP17L3 →+0.039+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

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