Across TCGA pan-cancer cohorts, RPL23AP30 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL23AP30’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL23AP30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP30 is over-expressed in tumor.

KIRC, STAD, and LUAD are the cancer types where RPL23AP30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.043	<.001	7	view →
STAD	All	II,III,IV	+0.184	.001	4	view →
LUAD	All	All	+0.250	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RPL23AP30 RNA expression & survival · all RPL23AP30 data types