RPL23AP23

Across TCGA pan-cancer cohorts, RPL23AP23 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RPL23AP23 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RPL23AP23 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL23AP23 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SARC show a favorable association.

BLCA, THCA, and DLBC are the cancer types where RPL23AP23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.775	0.509	.001	46	view →
THCA	OS	Tertile	All	0.965	0.986	.015	21	view →
DLBC	DFS	Tertile	IV	0.251	0.862	.004	21	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
TGCT	DFS	Tertile	II,III,IV	0.644	0.947	.044	18	view →
SARC	DFS	Tertile	All	0.722	0.496	.027	18	view →
KIRC	OS	Median	All	0.556	0.672	.006	13	view →
UCS	OS	Tertile	IV	1.000	0.275	.022	12	view →
ACC	DFS	Tertile	All	0.141	0.587	.041	9	view →
LIHC	OS	Tertile	III,IV	0.270	0.732	.021	9	view →
LUSC	DFS	Tertile	III,IV	0.176	0.776	.024	9	view →
LAML	DFS	Median	All	0.534	0.246	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RPL23AP23–BLCA (OS)

Open the BLCA breakdown →