RPL23AP23

Across TCGA pan-cancer cohorts, RPL23AP23 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL23AP23’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL23AP23 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP23 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, STAD, and BRCA are the cancer types where RPL23AP23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP23 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.042	.007	4	view →
STAD	All	All	+0.268	.007	3	view →
BRCA	Female	All	+0.182	.030	2	view →
KICH	All	All	−0.039	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL23AP23–KIRC

Open the KIRC breakdown →