RPL23

Across TCGA patient cohorts, RPL23 protein abundance is significantly associated with the RNA expression of many other genes, with 14,823 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPL23-associated genes across cancer lineages are FCGR3B, CXCR1, and CEACAM3. Each is linked with RPL23 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPL23-to-partner and partner-to-RPL23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL23 versus FCGR3B in PDAC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23→partner) and Y-score (partner→RPL23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FCGR3B →	-1.635	-0.475	<.001	<.001	3	7
UCEC	CXCR1 →	-1.293	-0.366	<.001	<.001	3	7
LSCC	CEACAM3 →	-0.705	-0.277	<.001	<.001	3	7
LSCC	CXCR2 →	-1.053	-0.257	<.001	<.001	3	7
HNSC	FFAR2 →	-1.207	-0.344	.001	.003	3	6
LSCC	ADGRE3 →	-0.704	-0.268	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,823 associations by consensus.

RPL23 vs FCGR3B — PDAC

Explore this scatter interactively →