RPL23

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL23 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL23-associated genes across cancer lineages are Basophils and pDC. Each is linked with RPL23 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL23-to-partner and partner-to-RPL23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by RPL23-low versus RPL23-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23→partner) and Y-score (partner→RPL23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBasophils →+0.202+3.000.039.03721
UCECpDC →+0.089+3.010.001.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Basophils by RPL23 expression — UCEC

Box plot of Basophils in RPL23-low vs RPL23-high samples in UCEC.

Explore this box plot interactively →

Exploration