RPL22P21

Across TCGA patient cohorts, RPL22P21 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,734 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL22P21-associated proteins across cancer lineages are NCOR1, METTL16, and NCBP3. Each is linked with RPL22P21 in more than 3 cancer types. Because this analysis shows association rather than direction, both RPL22P21-to-partner and partner-to-RPL22P21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL22P21 versus NCOR1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22P21→partner) and Y-score (partner→RPL22P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCOR1 →	+0.260	+0.499	<.001	<.001	3	4
LSCC	METTL16 →	+0.246	+0.437	.001	.009	2	4
GBM	NCBP3 →	+0.220	+0.363	.002	.004	3	3
LSCC	ALKBH5_S64 →	+0.685	+0.555	<.001	<.001	3	3
OV	TOP1_S112 →	-0.914	-0.328	<.001	<.001	3	3
GBM	HNRNPLL →	+0.213	+0.383	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,734 associations by consensus.

RPL22P21 vs NCOR1 — GBM

Explore this scatter interactively →