Across TCGA patient cohorts, RPL22P12 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,431 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL22P12-associated proteins across cancer lineages are TOP2A, TOP2A_S1247, and TOP2A_S1377. Each is linked with RPL22P12 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPL22P12-to-partner and partner-to-RPL22P12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL22P12→partner) and Y-score (partner→RPL22P12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TOP2A →	+0.808	+0.649	<.001	<.001	3	7
LUAD	TOP2A_S1247 →	+0.937	+0.465	<.001	<.001	3	7
PDAC	TOP2A_S1377 →	+0.959	+0.569	.001	.002	3	7
BRCA	TPX2_S738 →	+0.768	+1.389	.004	.001	3	7
GBM	CPSF1 →	+0.228	+0.759	.003	.001	3	7
BRCA	TPX2 →	+0.735	+1.790	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,431 associations by consensus.

Exploration

RPL22P12 survival (RNA) · tumor vs normal (RNA) · all RPL22P12 data types