Q-omics provides the consensus-scored RPL22P11 profile across patient tissues and cancer cell-line models. RPL22P11 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, RPL22P11 is differentially expressed in 3, with the highest sampling consensus in BRCA. Additionally, RPL22P11 RNA expression shows 8,901 significant protein co-abundance associations, with the highest sampling consensus in BRCA. Together, these results highlight BRCA as cancer lineages where RPL22P11 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL22P11 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL22P11 survival associations across molecular data types. RPL22P11 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL22P11 RNA expression–survival associations across cancer types. High RPL22P11 expression shows unfavorable associations in BRCA, STAD and THYM, but favorable associations in KIRC, BLCA and TGCT. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .033). Together, the overview and detailed table identify BRCA as the clearest survival context for RPL22P11 RNA expression.
This table summarizes RPL22P11 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for RPL22P11. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL22P11 shows lower tumor expression in BRCA and THCA and higher tumor expression in THCA and KIRC. The BRCA box plot shows higher RPL22P11 RNA expression in normal versus tumor tissue (log2 FC = −0.065, t-test p < 0.001).
This table shows molecular features associated with RPL22P11 in patient tissues and cancer cell lines. In patient samples, RPL22P11 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.
