RPL21P71

Across TCGA pan-cancer cohorts, RPL21P71 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPL21P71’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RPL21P71 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL21P71 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

UCEC, COAD, and THCA are the cancer types where RPL21P71 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P71 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.305	.031	2	view →
COAD	All	II,III,IV	+0.193	.019	2	view →
THCA	Female	All	−0.100	.007	2	view →
BRCA	Female	All	−0.031	.047	2	view →
STAD	Male	III,IV	−0.263	.004	1	view →
LUSC	Male	III,IV	−0.202	.001	1	view →
LUAD	Female	All	−0.087	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPL21P71–UCEC

Open the UCEC breakdown →