RPL21P136

Across TCGA pan-cancer cohorts, RPL21P136 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL21P136 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPL21P136 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL21P136 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

ACC, MESO, and ESCA are the cancer types where RPL21P136 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	II,III,IV	0.333	0.804	<.001	54	view →
MESO	OS	Median	III,IV	0.443	0.661	.002	49	view →
ESCA	OS	Median	III,IV	0.728	0.412	<.001	36	view →
HNSC	DFS	Quartile	All	0.677	0.567	.016	25	view →
COAD	DFS	Quartile	IV	0.262	0.514	.014	22	view →
KIRC	DFS	Tertile	All	0.554	0.694	.007	20	view →
PRAD	OS	Median	All	0.729	1.000	<.001	14	view →
LUSC	DFS	Quartile	II,III,IV	0.390	0.795	.004	12	view →
LGG	OS	Tertile	All	0.934	0.849	.003	10	view →
PAAD	DFS	Median	All	0.544	0.420	.032	8	view →
LUAD	DFS	Median	III,IV	0.419	0.202	.015	8	view →
SKCM	OS	Median	All	0.377	0.258	.018	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL21P136–ACC (DFS)

Open the ACC breakdown →