ribosomal protein L21 pseudogene 136Genealiases: []
Q-omics provides the consensus-scored RPL21P136 profile across patient tissues and cancer cell-line models. RPL21P136 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RPL21P136 is differentially expressed in 6, with the highest sampling consensus in HNSC. Additionally, RPL21P136 RNA expression shows 13,649 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, HNSC, and UVM as cancer lineages where RPL21P136 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL21P136 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL21P136 survival associations across molecular data types. RPL21P136 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL21P136 RNA expression–survival associations across cancer types. High RPL21P136 expression shows unfavorable associations in ACC, MESO, COAD and KIRC, but favorable associations in ESCA and HNSC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RPL21P136 RNA expression.
This table summarizes RPL21P136 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPL21P136. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL21P136 shows higher tumor expression in HNSC, CHOL, READ, KIRC, COAD and KIRP. The HNSC box plot shows higher RPL21P136 RNA expression in tumor versus normal tissue (log2 FC = +0.101, t-test p = .003).
This table shows molecular features associated with RPL21P136 in patient tissues and cancer cell lines. In patient samples, RPL21P136 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
