RPL21P135

Across TCGA patient cohorts, RPL21P135 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPL21P135-associated GO terms across cancer lineages are Protein stabilization, Regulation of canonical Wnt signaling pathway, and Negative regulation of protein-containing complex assembly. Each is linked with RPL21P135 in more than 24 cancer types. Because this analysis shows association rather than direction, both RPL21P135-to-partner and partner-to-RPL21P135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by RPL21P135-low versus RPL21P135-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL21P135→partner) and Y-score (partner→RPL21P135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.064	+0.393	<.001	<.001	3	25
STAD	Regulation of canonical Wnt signaling pathway →	+0.052	+0.402	<.001	<.001	3	24
STAD	Negative regulation of protein-containing complex assembly →	+0.054	+0.388	<.001	<.001	3	24
STAD	Stem cell differentiation →	+0.048	+0.427	<.001	<.001	3	24
STAD	Protein localization to cytoplasmic stress granule →	+0.089	+0.455	<.001	<.001	3	24
STAD	Negative regulation of transferase activity →	+0.052	+0.380	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

Protein stabilization by RPL21P135 expression — STAD

Explore this box plot interactively →