RPL21P12

Across TCGA pan-cancer cohorts, RPL21P12 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL21P12 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPL21P12 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL21P12 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUSC show a favorable association.

KICH, BLCA, and LUSC are the cancer types where RPL21P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.842	0.980	.003	63	view →
BLCA	OS	Median	All	0.599	0.243	.001	63	view →
LUSC	OS	Quartile	II,III,IV	0.631	0.275	<.001	49	view →
KIRC	DFS	Tertile	IV	0.478	0.708	.007	44	view →
ACC	OS	Tertile	II,III,IV	0.334	0.634	.010	30	view →
PAAD	DFS	Median	All	0.336	0.543	.004	23	view →
CESC	OS	Quartile	All	0.878	0.760	.029	10	view →
LIHC	DFS	Tertile	All	0.203	0.342	.028	9	view →
OV	OS	Quartile	IV	0.261	0.619	.005	6	view →
ESCA	DFS	Median	II,III,IV	1.000	0.399	.013	6	view →
BRCA	DFS	Quartile	II,III,IV	0.852	0.901	.031	4	view →
PRAD	DFS	Median	All	0.921	0.864	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL21P12–KICH (OS)

Open the KICH breakdown →