RPL21P12

Across TCGA pan-cancer cohorts, RPL21P12 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL21P12’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL21P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL21P12 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

COAD, BLCA, and BRCA are the cancer types where RPL21P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL21P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.226	.001	7	view →
BLCA	Female	IV	+0.243	.013	3	view →
BRCA	All	III,IV	−0.084	.026	2	view →
THCA	All	All	−0.082	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL21P12–COAD

Open the COAD breakdown →