RPL21

Across TCGA patient cohorts, RPL21 protein abundance is significantly associated with the RNA expression of many other genes, with 17,518 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPL21-associated genes across cancer lineages are JAM2, KLHDC1, and AKT3. Each is linked with RPL21 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPL21-to-partner and partner-to-RPL21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL21 versus JAM2 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL21→partner) and Y-score (partner→RPL21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JAM2 →	-1.081	-0.267	<.001	<.001	3	8
BRCA	KLHDC1 →	-0.780	-0.317	<.001	<.001	3	8
OV	AKT3 →	-0.987	-0.318	<.001	<.001	3	7
CCRCC	MYCT1 →	-1.111	-0.313	<.001	<.001	3	7
UCEC	ABCA8 →	-1.017	-0.242	<.001	<.001	3	7
HNSC	ABCA9 →	-1.240	-0.261	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,518 associations by consensus.

RPL21 vs JAM2 — UCEC

Explore this scatter interactively →