Across TCGA pan-cancer cohorts, RPL19P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL19P1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPL19P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL19P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
COAD and THCA are the cancer types where RPL19P1 tumor–normal differential expression is most reproducible.