RPL19

Across TCGA patient cohorts, RPL19 mutation is significantly associated with the RNA expression of many other genes, with 1,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL19-associated genes across cancer lineages are MMD2, LINC00314, and RNA5SP456. Each is linked with RPL19 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL19-to-partner and partner-to-RPL19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMD2 grouped by RPL19-low versus RPL19-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL19→partner) and Y-score (partner→RPL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MMD2 →	+0.037	+4.364	.002	.006	3	1
CESC	LINC00314 →	+0.073	+4.669	<.001	.007	3	1
CESC	RNA5SP456 →	+0.336	+5.342	<.001	.002	3	1
CESC	RNU6-335P →	+0.807	+4.234	<.001	.008	3	1
CESC	LINC01821 →	+0.121	+4.276	<.001	.008	3	1
CESC	FARSBP1 →	+0.038	+4.669	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,153 associations by consensus.

MMD2 by RPL19 expression — CESC

Explore this box plot interactively →