RPL18A

Across TCGA patient cohorts, RPL18A protein abundance is significantly associated with the RNA expression of many other genes, with 11,729 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RPL18A-associated genes across cancer lineages are ZNF540, N4BP2L1, and APBB1. Each is linked with RPL18A in more than 5 cancer types. Because this analysis shows association rather than direction, both RPL18A-to-partner and partner-to-RPL18A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL18A versus ZNF540 in LUAD, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL18A→partner) and Y-score (partner→RPL18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF540 →	-0.669	-0.299	<.001	<.001	3	6
COAD	N4BP2L1 →	-0.657	-0.206	.001	.007	3	6
HNSC	APBB1 →	-0.637	-0.175	<.001	<.001	3	6
OV	CARF →	-0.502	-0.198	.003	.004	3	5
GBM	TMEM144 →	-1.706	-0.404	<.001	<.001	3	5
LSCC	ZSCAN18 →	-0.667	-0.186	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,729 associations by consensus.

RPL18A vs ZNF540 — LUAD

Explore this scatter interactively →