RPL15

Across TCGA patient cohorts, RPL15 mutation is significantly associated with the RNA expression of many other genes, with 468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL15-associated genes across cancer lineages are RNA5SP131, IGLVIV-53, and GPATCH11. Each is linked with RPL15 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL15-to-partner and partner-to-RPL15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP131 grouped by RPL15-low versus RPL15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL15→partner) and Y-score (partner→RPL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP131 →	+0.306	+3.092	<.001	.002	3	2
SKCM	IGLVIV-53 →	+0.094	+7.816	<.001	.008	3	2
UCEC	GPATCH11 →	+0.442	+2.711	.009	.003	3	1
UCEC	CAPSL →	-2.098	-3.576	.001	.002	3	1
UCEC	STK32B →	+0.927	+3.584	.004	.002	3	1
UCEC	NUS1 →	+0.579	+2.721	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 468 associations by consensus.

RNA5SP131 by RPL15 expression — UCEC

Explore this box plot interactively →