RPL13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL13 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL13-associated genes across cancer lineages are MIR4727, MIR98, and OR8A3P. Each is linked with RPL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL13-to-partner and partner-to-RPL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4727 grouped by RPL13-low versus RPL13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL13→partner) and Y-score (partner→RPL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR4727 →+0.825+6.484<.001<.00132
UCECMIR98 →+0.358+3.386.003.00832
SKCMOR8A3P →+0.139+4.513<.001.00932
LUSCMIR6724-2 →+0.694+7.924<.001.00832
SKCMCLCP1 →+0.158+4.680<.001.00732
BLCANARS1P2 →+0.175+5.836<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

MIR4727 by RPL13 expression — BLCA

Box plot of MIR4727 in RPL13-low vs RPL13-high samples in BLCA.

Explore this box plot interactively →

Exploration