Charcot-Leyden crystal protein pseudogene 1Genealiases: []
Q-omics provides the consensus-scored CLCP1 profile across patient tissues and cancer cell-line models. CLCP1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, CLCP1 is differentially expressed in 2, with the highest sampling consensus in THCA. Additionally, CLCP1 RNA expression shows 11,927 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight THYM, THCA, and GBM as cancer lineages where CLCP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CLCP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CLCP1 survival associations across molecular data types. CLCP1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CLCP1 RNA expression–survival associations across cancer types. High CLCP1 expression shows unfavorable associations in THYM, READ, ESCA and THCA, but favorable associations in LAML and LUAD. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for CLCP1 RNA expression.
This table summarizes CLCP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for CLCP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CLCP1 shows lower tumor expression in THCA and higher tumor expression in LIHC. The THCA box plot shows higher CLCP1 RNA expression in normal versus tumor tissue (log2 FC = −0.112, t-test p < 0.001).
This table shows molecular features associated with CLCP1 in patient tissues and cancer cell lines. In patient samples, CLCP1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
