RPL12P45

Across TCGA pan-cancer cohorts, RPL12P45 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RPL12P45 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL12P45 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL12P45 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

KIRC, TGCT, and KICH are the cancer types where RPL12P45 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.372	0.585	<.001	98	view →
TGCT	OS	Tertile	All	0.754	0.991	<.001	90	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
SKCM	DFS	Tertile	III,IV	0.254	0.618	<.001	60	view →
HNSC	OS	Tertile	All	0.497	0.327	.013	33	view →
BLCA	OS	Tertile	All	0.896	0.550	.030	30	view →
GBM	DFS	Tertile	All	0.075	0.259	.001	18	view →
THYM	DFS	Tertile	II,III,IV	0.632	0.885	.014	18	view →
CESC	DFS	Tertile	IV	0.208	0.584	.010	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
LAML	DFS	Tertile	All	0.411	0.655	.013	14	view →
ESCA	DFS	Quartile	II,III,IV	0.134	0.900	.012	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RPL12P45–KIRC (OS)

Open the KIRC breakdown →