RPL12P45

Across TCGA pan-cancer cohorts, RPL12P45 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL12P45’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL12P45 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL12P45 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA and KIRC are the cancer types where RPL12P45 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL12P45 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.022	.048	2	view →
KIRC	Male	All	+0.010	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL12P45–BRCA

Open the BRCA breakdown →