RPL12P33

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL12P33 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL12P33 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPL12P33 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL12P33 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

ACC, OV, and SKCM are the cancer types where RPL12P33 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianAll0.2320.632<.00183view →
OVOSTertileAll0.2700.368.00530view →
SKCMOSTertileAll0.8270.681.00229view →
SARCOSTertileAll0.6300.822<.00128view →
CESCDFSTertileIII,IV0.7620.349.02914view →
CHOLOSQuartileAll0.8260.378.01613view →
PAADOSMedianII,III,IV0.6290.249.00512view →
ESCAOSMedianIV0.6980.222.00612view →
THCAOSTertileII,III,IV1.0000.971.0158view →
LUADOSTertileIII,IV0.2660.636.0078view →
KICHDFSMedianAll0.8090.971.0227view →
UVMDFSMedianAll0.6930.442.0416view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL12P33–ACC (DFS)

Kaplan–Meier survival curve for RPL12P33 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration