RPL12P33

Across TCGA pan-cancer cohorts, RPL12P33 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RPL12P33’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL12P33 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL12P33 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, KIRP, and HNSC are the cancer types where RPL12P33 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL12P33 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	+0.291	<.001	8	view →
KIRP	All	II,III,IV	+0.229	.002	7	view →
HNSC	Male	All	+0.269	.002	6	view →
COAD	All	All	+0.256	.007	4	view →
THCA	All	II,III,IV	+0.214	.021	4	view →
LIHC	All	All	+0.088	.007	3	view →
READ	All	III,IV	+0.554	.036	2	view →
CHOL	All	All	+0.270	.002	2	view →
LUSC	Male	II,III,IV	+0.200	.016	2	view →
PRAD	All	All	+0.182	.030	2	view →
KICH	All	All	−0.131	.039	2	view →
LUAD	All	All	+0.190	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RPL12P33–KIRC

Open the KIRC breakdown →