RPL10L

Across TCGA cell cohorts, RPL10L mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPL10L-associated genes across cancer lineages are GH1, R3HDML, and GDNF. Each is linked with RPL10L in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL10L-to-partner and partner-to-RPL10L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GH1 grouped by RPL10L-low versus RPL10L-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL10L→partner) and Y-score (partner→RPL10L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GH1 →	+0.062	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	R3HDML →	+0.146	+3.536	<.001	.001	3	1
BLOOD_Leukemia	GDNF →	+0.076	+4.000	<.001	.004	3	1
BLOOD_Leukemia	KRT6C →	+0.017	+4.037	<.001	.004	3	1
BLOOD_Leukemia	PROP1 →	+0.027	+3.874	<.001	.005	3	1
BLOOD_Leukemia	DIP2C-AS1 →	+0.124	+3.896	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GH1 by RPL10L expression — BREAST

Explore this box plot interactively →