RPL10L

Across TCGA pan-cancer cohorts, RPL10L RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL10L’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL10L RNA is repressed in tumor relative to normal tissue. In most cancer types RPL10L is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, READ, and KIRC are the cancer types where RPL10L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL10L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−1.756	<.001	11	view →
READ	Male	All	−1.890	<.001	6	view →
KIRC	Male	All	+0.083	<.001	6	view →
LIHC	All	All	+0.301	<.001	4	view →
PRAD	All	All	+0.156	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPL10L–COAD

Open the COAD breakdown →