RPL10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL10 mutation is significantly associated with the RNA expression of many other genes, with 3,252 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL10-associated genes across cancer lineages are BCCIP, TAF9, and UHRF1. Each is linked with RPL10 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPL10-to-partner and partner-to-RPL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by RPL10-low versus RPL10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL10→partner) and Y-score (partner→RPL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBCCIP →+0.374+2.370.003.00333
UCECTAF9 →+0.559+3.021<.001<.00132
UCECUHRF1 →+1.011+3.010<.001<.00132
UCECZNF670 →+0.470+2.859.007.00132
LGGUSP9YP10 →+0.049+7.977<.001.00732
BLCAARAFP1 →+0.048+5.040<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,252 associations by consensus.

BCCIP by RPL10 expression — UCEC

Box plot of BCCIP in RPL10-low vs RPL10-high samples in UCEC.

Explore this box plot interactively →

Exploration