RPH3A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPH3A protein abundance is significantly associated with the RNA expression of many other genes, with 5,903 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPH3A-associated genes across cancer lineages are PAK5, SLC1A2, and PRMT8. Each is linked with RPH3A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPH3A-to-partner and partner-to-RPH3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPH3A versus PAK5 in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPH3A→partner) and Y-score (partner→RPH3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPAK5 →+0.762+0.542<.001<.00132
GBMSLC1A2 →+1.236+0.575<.001<.00132
GBMPRMT8 →+0.847+0.790<.001<.00132
GBMPEX5L →+1.551+0.665<.001<.00132
GBMCBLN2 →+1.124+0.766<.001<.00132
PDACCPB1 →+3.599+0.289<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,903 associations by consensus.

RPH3A vs PAK5 — GBM

Per-sample scatter of RPH3A vs PAK5 in GBM (Pearson r = 0.43).

Explore this scatter interactively →

Exploration