RPGR

Across TCGA patient cohorts, RPGR protein abundance is significantly associated with the protein abundance of many other proteins, with 8,216 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPGR-associated proteins across cancer lineages are CEP135, DAXX_S495, and MMP8. Each is linked with RPGR in more than 3 cancer types. Because this analysis shows association rather than direction, both RPGR-to-partner and partner-to-RPGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPGR versus CEP135 in UCEC, with a Pearson correlation of 0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPGR→partner) and Y-score (partner→RPGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CEP135 →	+0.447	+0.382	<.001	<.001	3	4
OV	DAXX_S495 →	-0.593	-1.172	<.001	<.001	3	4
GBM	MMP8 →	+1.336	+0.361	<.001	<.001	3	4
UCEC	RPGR_S518 →	+0.771	+0.458	<.001	<.001	3	4
UCEC	CRISP3 →	+0.808	+0.380	<.001	.002	3	4
GBM	PRTN3 →	+1.123	+0.289	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,216 associations by consensus.

RPGR vs CEP135 — UCEC

Explore this scatter interactively →