RPGR

Across TCGA cell cohorts, RPGR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,381 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPGR-associated GO terms across cancer lineages are Protein localization to non-motile cilium, Intraciliary transport, and Protein localization to cilium. Each is linked with RPGR in more than 16 cancer types. Because this analysis shows association rather than direction, both RPGR-to-partner and partner-to-RPGR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to non-motile cilium grouped by RPGR-low versus RPGR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPGR→partner) and Y-score (partner→RPGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein localization to non-motile cilium →	+0.091	+0.830	<.001	<.001	3	17
SOFT_TISSUE	Intraciliary transport →	+0.082	+0.920	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Protein localization to cilium →	+0.068	+0.846	<.001	<.001	3	15
PANCREAS	Photoreceptor cell development →	+0.078	+0.817	.003	.001	3	13
BLOOD_Myeloma	Regulation of heterochromatin formation →	+0.083	+0.642	.004	.005	3	12
LUNG_SCLC	Transport along microtubule →	+0.055	+0.725	.003	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,381 associations by consensus.

Protein localization to non-motile cilium by RPGR expression — SOFT_TISSUE

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