Across TCGA patient cohorts, RPF2 mutation is significantly associated with the RNA expression of many other genes, with 494 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPF2-associated genes across cancer lineages are RNA5SP124, RNU6-454P, and RNU6-797P. Each is linked with RPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPF2-to-partner and partner-to-RPF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPF2→partner) and Y-score (partner→RPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP124 →	+0.410	+2.166	<.001	.008	3	2
SKCM	RNU6-454P →	+0.268	+4.594	<.001	.008	3	2
READ	RNU6-797P →	+0.381	+5.421	<.001	.005	3	1
READ	RNU6-335P →	+0.361	+5.039	<.001	.008	3	1
READ	RNU6-399P →	+0.428	+5.653	<.001	.003	3	1
READ	RNU6-285P →	+0.577	+5.925	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 494 associations by consensus.

Exploration

RPF2 survival (RNA) · tumor vs normal (RNA) · all RPF2 data types