RPEP4

Across TCGA patient cohorts, RPEP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,653 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPEP4-associated GO terms across cancer lineages are Peptidyl-lysine modification, Regulation of post-translational protein modification, and Positive regulation of double-strand break repair. Each is linked with RPEP4 in more than 18 cancer types. Because this analysis shows association rather than direction, both RPEP4-to-partner and partner-to-RPEP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by RPEP4-low versus RPEP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPEP4→partner) and Y-score (partner→RPEP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine modification →	+0.056	+0.353	<.001	<.001	3	19
STAD	Regulation of post-translational protein modification →	+0.060	+0.379	<.001	<.001	3	19
STAD	Positive regulation of double-strand break repair →	+0.053	+0.358	<.001	<.001	3	19
STAD	DNA modification →	+0.050	+0.352	<.001	<.001	3	19
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.067	+0.374	<.001	<.001	3	18
ESCA	Negative regulation of RNA catabolic process →	+0.055	+0.469	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,653 associations by consensus.

Peptidyl-lysine modification by RPEP4 expression — STAD

Explore this box plot interactively →