RPEP4

Across TCGA pan-cancer cohorts, RPEP4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPEP4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPEP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPEP4 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.

COAD, KIRC, and HNSC are the cancer types where RPEP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPEP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.077	.013	8	view →
KIRC	All	All	+0.042	.011	4	view →
HNSC	Female	IV	+0.090	.032	1	view →
LIHC	Female	All	−0.017	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPEP4–COAD

Open the COAD breakdown →