RPEP2

Across TCGA patient cohorts, RPEP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,108 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPEP2-associated GO terms across cancer lineages are Calcium ion export across plasma membrane, Protein N-linked glycosylation, and Negative regulation of autophagy. Each is linked with RPEP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RPEP2-to-partner and partner-to-RPEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion export across plasma membrane grouped by RPEP2-low versus RPEP2-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPEP2→partner) and Y-score (partner→RPEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Calcium ion export across plasma membrane →	+0.084	+0.004	<.001	.005	3	4
STAD	Protein N-linked glycosylation →	+0.090	+0.056	<.001	<.001	3	4
STAD	Negative regulation of autophagy →	+0.084	+0.063	<.001	<.001	3	4
STAD	Carbohydrate catabolic process →	+0.086	+0.028	<.001	<.001	3	4
STAD	Regulation of reactive oxygen species metabolic process →	+0.080	+0.030	<.001	<.001	3	4
STAD	Positive regulation of cysteine-type endopeptidase activity →	+0.080	+0.031	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,108 associations by consensus.

Calcium ion export across plasma membrane by RPEP2 expression — BRCA

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