Q-omics provides the consensus-scored RPEP2 profile across patient tissues and cancer cell-line models. RPEP2 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, RPEP2 RNA expression shows 5,733 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight ESCA, and LUSC as cancer lineages where RPEP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RPEP2 survival associations across molecular data types. RPEP2 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RPEP2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	ESCA (36)	view →

This table ranks reproducible RPEP2 RNA expression–survival associations across cancer types. High RPEP2 expression shows unfavorable associations in ESCA, STAD, DLBC, TGCT, BRCA and LUSC. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for RPEP2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
STAD	OS	Tertile	II,III,IV	0.513	0.732	.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
TGCT	DFS	Tertile	All	0.059	0.802	<.001	18	view →
BRCA	DFS	Tertile	All	0.724	0.903	.031	12	view →
LUSC	OS	Tertile	All	0.372	0.677	.037	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

RPEP2-ESCA (OS)

Kaplan–Meier survival curve for RPEP2 RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RPEP2 in patient tissues and cancer cell lines. In patient samples, RPEP2 shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,733	LUSC (2413)	view →
Function (RNA)	5,108	STAD (4950)	view →