RPARP-AS1

Across TCGA patient cohorts, RPARP-AS1 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPARP-AS1-associated genes across cancer lineages are RNU6-1284P, RNA5SP516, and RN7SKP204. Each is linked with RPARP-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPARP-AS1-to-partner and partner-to-RPARP-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1284P grouped by RPARP-AS1-low versus RPARP-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPARP-AS1→partner) and Y-score (partner→RPARP-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1284P →	+0.732	+5.186	.003	.007	3	1
UCEC	RNA5SP516 →	+0.877	+5.937	<.001	.002	3	1
UCEC	RN7SKP204 →	+0.811	+4.982	<.001	.009	3	1
UCEC	RNU1-28P →	+0.519	+5.484	.004	.005	3	1
UCEC	RNU6-1324P →	+1.033	+4.982	<.001	.009	3	1
UCEC	RNU6-1122P →	+0.922	+5.358	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

RNU6-1284P by RPARP-AS1 expression — UCEC

Explore this box plot interactively →