RPAP3

Across TCGA patient cohorts, RPAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,902 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPAP3-associated genes across cancer lineages are CENPF, LMOD1, and NEK2. Each is linked with RPAP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPAP3-to-partner and partner-to-RPAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPAP3 versus CENPF in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP3→partner) and Y-score (partner→RPAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CENPF →	+1.174	+0.204	<.001	.001	3	8
OV	LMOD1 →	-1.082	-0.295	.001	<.001	3	8
GBM	NEK2 →	+1.069	+0.250	<.001	<.001	3	7
OV	CNRIP1 →	-0.773	-0.256	<.001	.002	3	7
LSCC	PDCD2L →	+0.740	+0.252	<.001	<.001	3	7
UCEC	CDCA8 →	+1.210	+0.241	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,902 associations by consensus.

RPAP3 vs CENPF — GBM

Explore this scatter interactively →