RPAP3

Across TCGA cell cohorts, RPAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,489 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPAP3-associated GO terms across cancer lineages are Sister chromatid cohesion, Nuclear chromosome segregation, and Nuclear pore organization. Each is linked with RPAP3 in more than 16 cancer types. Because this analysis shows association rather than direction, both RPAP3-to-partner and partner-to-RPAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid cohesion grouped by RPAP3-low versus RPAP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP3→partner) and Y-score (partner→RPAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Sister chromatid cohesion →	+0.128	+0.595	.002	.002	3	17
STOMACH	Nuclear chromosome segregation →	+0.113	+0.711	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.181	+1.002	<.001	<.001	3	17
CNS	Nuclear division →	+0.083	+0.659	<.001	<.001	3	17
BONE	DNA-templated DNA replication →	+0.164	+0.763	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.137	+1.036	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,489 associations by consensus.

Sister chromatid cohesion by RPAP3 expression — BONE

Explore this box plot interactively →