RPAP2

Across TCGA patient cohorts, RPAP2 mutation is significantly associated with the RNA expression of many other genes, with 1,645 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPAP2-associated genes across cancer lineages are MTND1P22, SCARNA21B, and RN7SL811P. Each is linked with RPAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPAP2-to-partner and partner-to-RPAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND1P22 grouped by RPAP2-low versus RPAP2-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPAP2→partner) and Y-score (partner→RPAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MTND1P22 →	+0.139	+5.039	<.001	.008	3	2
READ	SCARNA21B →	+0.476	+5.039	<.001	.008	3	2
READ	RN7SL811P →	+0.137	+5.653	<.001	.003	3	2
LUAD	RNU6-519P →	+0.620	+4.481	<.001	.005	3	2
BLCA	RNU6-1228P →	+0.196	+4.122	<.001	.008	3	2
BLCA	LRRC57P1 →	+0.131	+3.435	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,645 associations by consensus.

MTND1P22 by RPAP2 expression — READ

Explore this box plot interactively →